Analysis of risk factors in patients with nonvalvular atrial fibrillation

Abstract

Objective To investigate the correlation between stroke and the race, age, gender, smoking and drinking habits, oral antithrombotic drugs, chronic diseases in patients with nonvalvular atrial fibrillation. Methods Four thousand four hundred and ninety patients with nonvalvular atrial fibrillation were collected from 13 different hospitals in Xinjiang Uygur Autonomous Region from October 2013 to October 2014.All the patients were divided into two groups, nonvalvular atrial fibrillation alone group(n=3 653)and nonvalvular atrial fibrillation with stroke group(n=837), by the means of improving the skulls CT and/or MRI test.Then the race, gender, age, drinking and smoking habits, oral anticoagulants using, aspirin using, diabetes, hypertension, coronary heart disease, chronic lung disease, chronic kidney disease, chronic liver disease were compared between the 2 groups. Results ①The differences were statistically significant(P 74 years 74.6% vs.25.4%, P 0.05). ③Logistic regression analysis showed that the race of Han, increasing age, aspirin use, hypertension were independent risk factors of stroke in the patients with nonvalvular atrial fibrillation, while the habit of drinking might be a protective factors.There was no obvious correlation between smoking 87.1% vs 91.6%, occasional drinking 10.3% vs 6.7%, frequdnthy drink 2.7% vs 1.7%, P 0.05). ③Logistic regression analysis showed that the race of Han, increasing age, aspirin use, hypertension were independent risk factors of stroke in the patients with nonvalvular atrial fibrillation, while the habit of drinking might be a protective factors.There was no obvious correlation between smoking habits, diabetes, coronary heart disease and the increased risk of stroke in the patients with nonvalvular atrial fibrillation. Conclusion Our analysis suggests that increasing age, hypertension, aspirin use are the independent risk factors of stroke in the patients with nonvalvular atrial fibrillation, but the habit of drinking may be a protective factor. Key words: Atrial fibrillation; Stroke; Race; Smoking; Drinking