Analysis of risk factors affecting biochemical test results

Abstract

Objective To explore the risk factors affecting biochemical indicators . Methods The data of 120 patients undergoing biochemical examinations in Liaocheng Third People's Hospital during the period of September 2016 and November 2017 was analyzed retrospectively. The factors affecting the results of biochemical tests were analyzed by the Logistic regression line. At the same time, the levels of creatine kinase, lactate dehydrogenase, and blood potassium were observed and compared at the initial examination and reexamination. The levels of blood sodium, blood sugar, and blood potassium were observed under the different blood sampling methods. And the blood sugar, urea, and chloride levels were observed. Results Age, sex, diet, exercise, medicine, and environment could affect the biochemical test results before the examination; the time of specimen collection, operation, preservation, and inspection could affect the biochemical test results during the examination; the treatment of specimens, instrument, and biochemical reagent could affect the biochemical test results after the examination. The contents of hemolytic blood potassium, lactate dehydrogenase, creatine kinase at the initial examination were (7.1±1.8) mmol/L, (713.6±50.9) U/L, (263.1±30.8) U/L, those at the reexamination were (4.1±0.6) mmol/L, (143.6±20.9) U/L, (52.1±10.8) U/L, those at the initial examination were significantly higher (P<0.05). The contents of blood sodium, blood sugar, and blood potassium under the contralateral blood sampling were (132.1±15.3) mmol/L, (6.6±0.9) mmol/L, (4.1±0.3) mmol/L, those under the ipsilateral blood sampling were (152.3±13.2) mmol/L, (23.6±4.9) mmol/L, (7.2±1.8) mmol/L, those under the ipsilateral blood sampling were significantly higher (P<0.05). The contents of chlorine ion, blood sugar, urea were (28.6±4.6) mmol/L, (0.8±0.1) mmol/L, (0.5±0.1) mmol/L when the fibrin had not been precipitated, those were (104.2±16.5) mmol/L, (6.5±1.3) mmol/L, (6.1±1.5) mmol/L when the fibrin had been precipitated, those were obviously lower when the fibrin had not been precipitated (P<0.05). Conclusion There are factors that affect the results of clinical biochemical testing before, during and after biochemical analysis. Therefore, the quality of biochemical testing should be strengthened and the accuracy of biochemical test results should be improved effectively. Key words: Biochemical indicator; Detection result; Risk factor; Logistic regression analysis