Abstract
BackgroundTo evaluate the rate, risk factors, functional outcome and prognosis in eyes with retinal detachment after post-operative endophthalmitis treated with 23G Pars Plana Vitrectomy.MethodsElectronic patient files from 2009 until 2018 were screened for the presence of an endophthalmitis. Included were 116 eyes of 116 patients. This population was evaluated for the rate of retinal detachment after 23G Pars Plana Vitrectomy for endophthalmitis following cataract surgery or intravitreal injection. The main outcome measures were retinal detachment and visual acuity.ResultsThe reasons for endophthalmitis were previous cataract surgery in 78 patients and following intravitreal injection in 38 patients. The first clinical evidence of endophthalmitis was present in median 5 days after the triggering intervention. Twenty-five eyes (21.55%) developed a retinal detachment an average of 25 days after endophthalmitis. RD is significantly associated with preoperative visual acuity (p = 0.001).ConclusionsWe emphasize the prognostic role of preoperative visual acuity in RD development of the endophthalmitis treated with 23G Pars Plana Vitrectomy.
Highlights
To evaluate the rate, risk factors, functional outcome and prognosis in eyes with retinal detachment after post-operative endophthalmitis treated with 23G Pars Plana Vitrectomy
Retinal detachment (RD) was related to capsular rupture, noxious bacteria and an early additional procedure in the Endophthalmitis Vitrectomy Study (EVS)
Patients were diagnosed with endophthalmitis if they presented with characteristic endophthalmitis symptoms and signs within 6 weeks following cataract surgery or intravitreal injection
Summary
Risk factors, functional outcome and prognosis in eyes with retinal detachment after post-operative endophthalmitis treated with 23G Pars Plana Vitrectomy. Endophthalmitis (EO) is a severe intraocular inflammatory response It is typically divided into exogenous, endogenous (systemic infection in an immune-compromised patient), or masquerade syndromes (large cell lymphoma). Exogenous is mostly postoperative (e.g., cataract surgery), but may be post-traumatic or related to organisms with an ability to penetrate intact corneas It can be classified as either culture-positive or culture-negative (sterile) [1, 2]. RD was related to capsular rupture, noxious bacteria and an early additional procedure in the Endophthalmitis Vitrectomy Study (EVS). It led to a poor visual prognosis, with 27% of patients achieving a final best corrected visual acuity (BCVA) of 20/40 [10]. The EVS showed that early vitrectomy yielded better results when visual acuity had dropped to LP
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