Analysis Of Rat Platelet Count After Electrical Exposure In Acute And Subacute Phase Of Burn Injury

Abstract

Electrical burns are one of the causes of important health burdens throughout the world with incidences varying between 4 – 18% of all burns. In electrical burns, blood vessels are the heavily damaged tissue characterized by endothelial erosion, followed by adhesion and aggregation of platelet to form hemostatic plug. The screening test for assesing the formation of a hemostatic plug is platelet count. Platelet count monitoring is very important during the resuscitation phase and treatment periods in severe burns, namely in acute and subacute phase of burns. The purpose of this study is to determine and to analyze about the changes in platelet count of rat after electrical exposure in acute and subacute phase of burns. The control group in this study was not given electrical exposure and rat’s blood was taken directly after the adaptation process. In the other five groups, P1, P2, P3, P4 and P5 were exposed to 140 V for 17 seconds, then their blood was taken for platelet counts on days 0, 3, 7, 10 and 14 post-exposure. The result of this study based on Post Hoc LSD test showed that there was a change of platelet platelet number after exposure in acute phase of burn injury and there was no change of platelet platelet number after exposure in burning subacute phase.