Abstract

The rheologic effects of multiple “non-obstructive” plaques in main coronary arteries of man were examined by numerically solving the fluid dynamic equations of motion for pulsatile viscous flow of blood through an arterial section using the actual variation of flow rate during the cardiac cycle. Flow regions identified by the calculations include spatial flow acceleration, deceleration, separation, reattachment and redevelopment. Shear stresses exerted by flowing blood on the endothelial surface varied greatly during the cardiac cycle, and there were large variations in shear stress along plaques. Wall shear stresses were relatively large even in regions of mild constriction. The computer program can be utilized in conjunction with coronary angiography to study the flow field for plaques of various sizes and shapes and with variable longitudinal spacing to obtain the level of wall shear stress and to determine the existence and extent of separated flow regions.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.