Analysis of progression with PeriDataTM and guided progression analysis (GPA) in glaucoma patients: interim analysis

Abstract

Abstract Purpose To compare the rate of progression of GPA with the progression analysis calculated by PeriData in a mixed glaucoma group. Methods Retrospective, observational study including 32 eyes (number needed: 76 eyes) of 17 known glaucoma patients with at least 5 reliable visual field examinations in minimum 2 years. Patients who underwent filtering surgery or laser trabeculoplasty during the follow‐up period were excluded. Results Mean age was 70 ±18 yrs. Each patient performed a mean number of 13 ±4.6 (range: 9 to 28) standard automated perimetry visual test (Sita Standard 24‐2) per eye and with a mean follow‐up of 7.5 ± 1.3 yrs. The mean of progression by PeriData (dB/year) and GPA (%/year) were: ‐0.2 ± 0.38 and ‐0.55 ± 0.71 respectively. This difference in progression was not significantly different (p value= 0.06) There was an excellent correlation between Peridata progression analysis and GPA (<0.001). Conclusion Rate of progression with GPA and progression analysis of PeriData are two trend analysis. This could explain the excellent correlation. They represent complementary information and methods for progression of VF. To date, our results didn’t show significant difference between GPA and PeriData.