Abstract
Analysis of Process Parameters and Performance Test for Fabricating Stainless-steel Metal Microneedles
Highlights
Puncturing the skin deeply to deliver liquid drugs into the body of an organism through a hollow needle has been the most common invasive medical procedure for over 150 years.[1]
We proposed one novel, low-cost method of fabricating stainlesssteel metal microneedles by the hybrid method of mechanical dicing (MD) and electrochemical corrosion (EC).(18) the detailed fabrication process parameters are needed to be analyzed for their application
In this paper, the main process parameters of shaping microneedles, namely current and solution concentration of the EC, were discussed in detail, and the force test and transdermal drug delivery test were performed to evaluate the performances of these microneedles
Summary
Puncturing the skin deeply to deliver liquid drugs into the body of an organism through a hollow needle has been the most common invasive medical procedure for over 150 years.[1]. We proposed one novel, low-cost method of fabricating stainlesssteel metal microneedles by the hybrid method of mechanical dicing (MD) and electrochemical corrosion (EC).(18) the detailed fabrication process parameters are needed to be analyzed for their application. In this paper, the main process parameters of shaping microneedles, namely current and solution concentration of the EC, were discussed in detail, and the force test and transdermal drug delivery test were performed to evaluate the performances of these microneedles. The results of the force test and the transdermal drug delivery test demonstrated that the fabricated microneedles with the analyzed parameters were safe and practicable, as expected
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