Analysis of Prescription Rules of Neonatal Jaundice in 'Yibu Quanlu' Based on Data Mining

Abstract

Objective: To analyze the prescription rules for the treatment of neonatal jaundice in 'Yibu Quanlu' based on data mining technology. Methods: The provisions of the treatment of neonatal jaundice recorded in the 'Yibu Quanlu' were collected. Through the collation and entry of the ancient and modern medical case cloud platform, the data included in the medical case were standardized, and then the standardized prescription database was generated. Finally, the data analysis module in the platform was used to process the frequency statistics, association rule analysis, cluster analysis and complex network analysis of traditional Chinese medicine. Results: Included in 57 provisions (including 6 ancient medical cases), 67 prescriptions of traditional Chinese medicine, involving 112 herbs, the cumulative frequency of 751 times. The highest frequency of use of traditional Chinese medicine is licorice, followed by atractylodes, the average dose of traditional Chinese medicine is Yinchen; the taste is mainly bitter cold, followed by Ganping; most of them belong to the spleen, stomach and lung meridians. The use of moisturizing drugs is the most, followed by tonifying drugs; the Chinese herbal pair with the highest support was Poria – Atractylodes macrocephala; core Chinese medicine prescription is Yinchen Wuling Powder and Yigong Powder. Conclusion: A comprehensive analysis of prescription and medication rules for treating neonatal jaundice in 'Yibu Quanlu', and finds that clearing heat and removing dampness, protecting spleen and stomach, and preventing transmission become the main guiding ideology for the diagnosis and treatment of this disease. Eliminating pathogenic factors and strengthening vital energy are the main characteristics of prescription medication for ancient doctors. This study can provide new ideas for the clinical diagnosis and treatment of neonatal jaundice in modern Chinese medicine and the development of new drugs.