Analysis of photobiomodulation therapy conditions used to treat neurodegenerative brain diseases

Abstract

Many clinical trials on photobiomodulation (PBM) therapy from head to toe have been reported during the last 30 years. The benefits of PBM therapy (PBMT) include pain relief, wound healing, skin rejuvenation, hair growth, and reduction of inflammation, and etc. Recently, applications of PBMT on the nose and brain have shown to be effective in delaying the progress of the neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s diseases (PD). Various PBMT devices have been used to treat the neurodegenerative brain diseases, but the PBMT device structure, doses, irradiances, and light sources used for the clinical trials were different, which makes it difficult for users to find an appropriate treatment method. In this paper, diverse treatment methods for the neurodegenerative brain disease, and the most frequently used PBMT conditions were analyzed.