Analysis of pelvic and non-pelvic chondrosarcoma postoperative recurrence risk factors in 65 cases among 3 ethnic groups (Han, Uyghur, and other nationalities)

Abstract

Background: Chondrosarcomas are a rare tumor that has a variable biological characteristic, also their treatment clinically and surgically is controversial. So, authors are analyzing the related risk factors of influencing the postoperative recurrence of chondrosarcoma. Methods: Retrospective analysis of clinical data, a total of 65 cases of chondrosarcoma were collected from January 2002 to June 2016 in our hospital database and divided into 2 groups (pelvic and non-pelvic chondrosarcoma) with 3 ethnic class (Han, Uyghur, and other nationalities) of Chinese people. The clinical characteristics and prognostic risk factors of chondrosarcoma recurrence were analyzed by different statistic methods. Results: The age, sex, nationality, surgical method, pathological grade and Enneking stage of chondrosarcoma patients were not significantly correlated with postoperative recurrence (P>.05); but the site of tumor growth was significantly correlated with postoperative recurrence (P<0.001). Cox regression model multivariate analysis showed that tumor growth site was an independent factor influencing postoperative recurrence of chondrosarcoma, and the risk of postoperative recurrence of pelvic chondrosarcoma was 3.610 times higher than non-pelvic chondrosarcoma. Conclusion: The recurrence rate of pelvic chondrosarcoma was significantly higher than non-pelvic chondrosarcoma.