Abstract
Purpose: to compare the depth of anesthesia and hemodynamic reactions during general anesthesia for caesarean section. Materials and Methods: 45 pregnant women scheduled for caesarean section under general anesthesia were enrolled. All patients were divided into 3 groups (15 patients in each), depending on the general anesthetics. In the 1st group used sodium thiopental 5 mg / kg, in the 2nd sodium thiopental 5 mg / kg with sevoflurane (0.5 MAC), 3rd propofol 2.5 mg / kg. Mean arterial pressure (MAP) and index of AAI were estimated at six basic stages of the operation. Results: the highest rates of mean arterial pressure and AAI index were observed in the first group. Summary: the use of a mixture of thiopental sodium dose of 5 mg/kg with sevoflurane (0.5 MAC) or propofol dose of 2.5 mg / kg provide a sufficient surgical level of depth of anesthesia in the main stages of the operation; allow minimize hypertensive response for intubation and surgical trauma in comparison with the thiopental sodium dose of 5 mg/kg.
Highlights
Materials and Methods: 45 pregnant women scheduled for caesarean section under general anesthesia were enrolled
Mean arterial pressure (MAP) and index of AAI were estimated at six basic stages of the operation
Results: the highest rates of mean arterial pressure and AAI index were observed in the first group Summary: the use of a mixture of thiopental sodium dose of 5 mg/kg with sevoflurane (0.5 MAC) or propofol dose of 2.5 mg / kg provide a sufficient surgical level of depth of anesthesia in the main stages of the operation; allow minimize hypertensive response for intubation and surgical trauma in comparison with the thiopental sodium dose of 5 mg/kg
Summary
Цель: сравнить глубину анестезии и гемодинамических реакций при общей анестезии при кесаревом сечении. Материалы и методы: в исследование были включены 45 рожениц, которым в плановом порядке проводили общую анестезию при кесаревом сечении. Пациентки были разделены на 3 группы по 15 человек в зависимости от используемых общих анестетиков. В первой группе использовали тиопентал натрия 5 мг/кг, во второй – тиопентал натрия 5 мг/кг с севофлураном (до 0,5 МАК), в третьей – пропофол 2,5 мг/кг. Среднее артериальное давление и индекс AAI оценивались на шести основных этапах операции. Результаты: наиболее высокие показатели среднего артериального давления и индекса AAI отмечались в первой группе. Выводы: использование смеси тиопентала натрия 5 мг/кг с севофлураном или пропофола 2,5 мг/кг обеспечивает хирургический уровень глубины анестезии, уменьшает выраженность прессорной реакции в сравнении с дозировкой тиопентала натрия 5 мг/кг. Ключевые слова: анестезия, пропофол, тиопентал натрия, севофлуран
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