Abstract
Single stranded DNA- or RNA-protein complexes appear in a number of biological pathways, particularly those relating to DNA replication, gene regulation, and chromosome stability. Protein-nucleic acid binding in these complexes has been studied for some time, and a number of structures of these complexes exist; however, few consistent rules for binding have been determined. In particular, DNA and RNA conformation appears to vary widely, even when bound to homologous proteins (e.g., telomere end-binding proteins).
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