Abstract

Determination of NRAMP-1 protein levels using the enzyme link-immunosorbent assay technique in death, had comorbidities and severity of clinical symptoms of COVID-19 patients. Of the 62 patients who received treatment, 10 patients died with an average NRAMP-1 level of 650ng/ml and 52 patients who survive with an average NRAMP-1 level of 1065.26ng/ml. The results of the study also found that 34 patients had comorbidities with an average NRAMP-1 level of 838.82ng/ml and 28 patients without comorbidities with an average NRAMP-1 level of 1191.92ng/ml. Based on the severity of clinical symptoms in survive patients, 10 patients with mild were found with an average NRAMP-1 level of 984.31ng/ml, with moderate in 31 patients with an average NRAMP-1 level of 1104.71ng/ml and severe in 11 patients with an average NRAMP-1 level of 1027.71ng/ml. NRAMP-1 protein levels were significantly lower in COVID-19 patients who died and had comorbidities.

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