Analysis of monitoring data on congenital heart disease in Shenzhen city from 2009 to 2013

Abstract

Objective To analyze monitoring data on congenital heart disease (CHD) in Shenzhen city from 2009 to 2013. Methods This study described epidemiological characteristics of perinatal CHD. Patients with CHD were divided into isolated CHD group and complex CHD group (the patients were found with malformations of other systems). The prognosis, social and demographic characteristics, and complications of pregnancy were analyzed. Results The average incidence rate of CHD was 7.25‰, of which 94.36% were diagnosed by ultrasound, of which 33.20% were diagnosed before delivery. The top three cardiovascular abnormalities were patent ductus arteriosus, patent foramen ovale, and ventricular septal defect. There were about 14.11% of CHD with other system malformations, mainly including musculoskeletal system, facial features, and nervous system. Compared isolated cardiac malformations and complex cardiac-malformations, significant differences were found in the age stratification, culture degree, prognosis, diagnosis time, incidence rate of complication of pregnancy, and childbirth complications rate (P<0.01). Conclusions Most CHDs were diagnosed by ultrasound. Simple cardiovascular malformation was common, especially CHD with two or more types of cardiovascular malformations. The incidence rate of CHD in 30 to 40-year-old women, stillbirth rate, incidence of prenatal diagnostic rate were significantly higher than the simple CHD group. Key words: Heart defects, Congenital/EP