Analysis of Midterm Outcomes of Endovascular Aneurysm Repair in Octogenarians From the ENGAGE Registry

Abstract

Data from a prospective, observational, international, multicenter, single-arm registry (Endurant Stent Graft Natural Selection Global postmarket registry [ENGAGE]) enlisted between March 2009 and April 2011 In patients >80 years (290 [23%]) vs <80 years (973 [77%]) who underwent endovascular aneurysm repair (EVAR), there were no significant differences in 30-day mortality (1.4% vs 1.2%), major adverse event rates (5.2% vs 3.6%), or freedom from secondary intervention during 5 years (89% vs 83%). However, age >80 years, pulmonary disease, large aneurysm diameter, and renal insufficiency were significantly associated with all-cause mortality. Freedom from all-cause mortality was significantly lower in the group >80 years (53%) than in the younger group (72%). EVAR can be performed in patients >80 years with no significant difference in midterm aneurysm-related deaths compared with younger patients. EVAR can be safely performed with acceptable morbidity rates in octogenarians.