Analysis of microorganism types composition in children with thermal injury

Abstract

Relevance. Burn wound is a damage of skin and mucous membranes integrity, which causes an immune system barrier and protective function disorder, making an «entrance gate» for microorganisms. That causes wound infection which is the main cause of death in children with burns. Burn wounds microflora is represented, as a rule, by associations of various conditionally pathogenic microorganisms. Purpose of the study: to study the microorganisms species composition in children with severe thermal injury, treated in a regional burn center. Materials and methods. We investigated biomaterial from 168 children, aged from 9 months to 17 years, with II-IIIAB degree burn wounds. Burn wounds area was from 20 to 70% of the body surface. 802 bacteriological culture samples were studied. Results and discussion. The most common cause of wound suppurative processes were gram-positive microorganisms. They were identified in 56,1% of cases. Gram-negative pathogens were found in 39,2% of cases. Fungi – in 4,75% of cases. Purulentseptic infectious processes in children with burns were predominantly caused by S. aureus (26,29%) and P. aeruginosa (13,5%). The associated infection was found in 56% of cases. Having analyzed S.aureus antibiogram we found sensivity to fusidic acid (100%), vancomycin (100%) and co-trimoxazole (86,4%); P. aeruginosa was sensitive to gentamicin (100%) and amikacin (64,7%). Conclusion . Children are at high risk of a generalized infection developing and require rational antibiotic therapy. Microbiological monitoring should be prtformed in a regional burn center.