Analysis of medication rule of Professor Yan Xiaocheng on the treatment of primary epilepsy

Abstract

Objective: To explore and analyze the medication rule of Professor Yan Xiaocheng in the treatment of primary epilepsy, hoping to provide reference for the clinical treatment of primary epilepsy. Method: Mining and analysis Professor Yan Xiaocheng sorted out the medical cases of primary epilepsy in Yan Xiaocheng’s Clinical experience Collection of Epilepsy,extracted the traditional Chinese medicine(TCM) prescription data in the medical cases, standardized the obtained TCM prescription data, and used the data mining function integrated by the ancient and modern medical case cloud platform V2.3.5 to carry out frequency statistics, cluster analysis, association analysis and complex network analysis on the TCM data, the common medicines used by Professor Yan Xiaocheng in the treatment of primary epilepsy, properties and classifications of commonly used medicines, pairs of commonly used medicines and coreprescriptions were obtained. Result: A total of 39 cases, 228 medical records and 192 prescriptions data of TCM were included. A total of Ill Chinese medicines were involved, and the total frequency of medication was 3190. High frequency medicines include Ramulus Uncariae cum Uncis (185 times), Rhizoma Gastrodiae (185 times), Rhizoma Acori Tatarinowii (178 times), Rhizoma Pinelliae Praeparatum (170 times), Bombyx Batryticatus (170 times) and cicada molting (151 times). The main properties and flavors of commonly used Chinese medicines were pungent, bitter and sweet, which were mainly attributed to the four meridians of liver, lung, heart and spleen. Commonly used couplet medicines were Cicada Molting-Bombyx Batryticatus, Rhizoma Acori Tatarinowii-Bombyx Batryticatus, Radix Bupleuri-Scutellaria, Rhizoma Gastrodiae-Ramulus Uncariae cum Uncis, Rhizoma Acori Tatarinowii-Cicada Molting, Ramulus Uncariae cum Uncis-Bombyx Batryticatus, etc. The core prescription composition was based on the addition and subtraction of Tianma Goutengtang and Erchentang. Conclusion: Professor Yan Xiaocheng’s medication for the treatment of primary epilepsy was based on the principle of relieving wind and spasm, drying dampness and resolving phlegm, giving consideration to both Qi and blood, and harmonizing liver, lung, heart and spleen.