Abstract
Background: Leprosy is a chronic disease caused by Mycobacterium leprae. Oxidative stress (OS) is a condition associated with an increased rate of celluler damage induced by the oxygen derived oxidants commonly known as reactive oxygen species (ROS). ROS are capable of damaging celluler constituen generated in excess during the chronic, inflammatory, and neurodegenerative disease process of leprosy. Malondialdehyde (MDA) is end product of lipid peroxidation by ROS and serves as marker of celluler damage. Aim: To analyse the diference of MDA level in Paucibacillary (PB) and Multibacillary (MB) leprosy. Methods: 17 new cases of leprosy patients that were diagnosed by clinical and laboratory examinations. We conducted blood samplings and measurements of plasma MDA level with HPLC method. Results: In this study, there was increased the mean of MDA level in MB compared with PB and significant statistically (p<0, 05). Conclusion: Tissue damage due to OS in leprosy patients is more severe in MB group than PB group
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Innovative Research in Medical Science
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
