Abstract
The age-adjusted death rates (AADRs) due to cancers were investigated in two historical regions of white wines (Tokaj and Balaton) and in Hódmezővásárhely (HMV) as a control territory in Hungary between 2000 and 2010 evaluating 111,910 persons. The results of AADRs due to the eight most frequent types/gastrointestinal cancers were as follows: Tokaj 2120/664, Balaton: 2417/824, HMV: 2770/821, nationwide: 2773/887. The values found in Tokaj and Balaton regions were significantly less than those of HMV and nationwide. However, the least values were found in Tokaj. This Tokaj-related strong difference was not found among the regions in the case of young populations with hematological diseases but only in the older people who have been consuming their wines for decades. Supposedly, this wine-specific anti-cancer phenomenon could be related to the chemical differences existing in the two types of white wines, namely, to the pro-oxidant molecules of Tokaj wines derived from Botrytis cinerea. The roles of red meat consumption, hardness of drinking water, mineral content of soil, and socioeconomic status were negligible. It should be stressed that these data are valid only for these populations, for this period. Noteworthily, the different types of wines may have different effects on mortality rates during long-lasting consumptions.
Highlights
In the present work, we compared the age-adjusted mortality rates (AADRs) due to cancers in two traditional white wine regions of Hungary and in a control, non-wine region in a large population who died between 2000 and 2011
The results on the hardness of drinking waters and cancer mortality values did not correlate to each other as could be seen from the following results: in Tokaj and HMV the drinking waters were of similar “soft character” (138.60 and 81.90 CaO mg/L), but the age-adjusted death rates (AADRs) values for gastrointestinal cancers were significantly different (664 versus 821, p = 0.009)
It is of note that comparing the AADR values of malignant lymphoid and hematological diseases already existing in childhood, there were differences in the whole population and in the persons who died under the age of 25 years
Summary
We compared the age-adjusted mortality rates (AADRs) due to cancers in two traditional white wine regions of Hungary and in a control, non-wine region in a large population who died between 2000 and 2011. Public Health 2020, 17, 6759; doi:10.3390/ijerph17186759 www.mdpi.com/journal/ijerph
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