Abstract

In order to improve the repair effect after peripheral nerve injury, this paper analyzes the related influencing factors. The regeneration of peripheral nerve includes two continuous and overlapping processes: the acute wound healing period and the axon seeking target tissue period. The complete and effective process of peripheral nerve regeneration includes the sprouting, growth and extension of regenerated axons, and the reconstruction of synaptic connections (neuromuscular junctions) with target organs to realize the reinnervation of nerves and restore function. This process includes three indicators of success in regeneration: structural reconstruction, metabolic regeneration, and functional recovery. In order to improve the repair effect of peripheral nerve injury, relevant influencing factors can be analyzed, and effective improvement of these influencing factors can improve the recovery effect of peripheral nerve injury. Finally, this paper analyzes multiple factors to provide theoretical references for follow-up clinical diagnosis and treatment.

Highlights

  • The frequency of peripheral nerve damage has increased significantly as my country’s industrial production mechanisation and transportation systems have improved

  • The existence of a suitable regeneration microenvironment determines the success of regeneration after injury [3]. Traditional neuroanastomosis methods such as epineurium, perineurium, and epineurium-perineurium anastomosis are commonly employed to restore the continuity of peripheral nerves after rupture

  • Based on the above analysis, important influencing variables may be studied in order to enhance the repair effect of peripheral nerve damage, and successful modification of these influencing factors can improve the recovery effect of peripheral nerve injury

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Summary

Introduction

The frequency of peripheral nerve damage has increased significantly as my country’s industrial production mechanisation and transportation systems have improved. The existence of a suitable regeneration microenvironment determines the success of regeneration after injury [3] Traditional neuroanastomosis methods such as epineurium, perineurium, and epineurium-perineurium anastomosis are commonly employed to restore the continuity of peripheral nerves after rupture. Many researchers have started to utilise autologous arteries and veins, amniotic membrane, nondegradable or degradable biological materials, and other materials to bridge the damaged ends of peripheral nerves. Patients with craniocerebral damage and peripheral nerve injury are examined at the clinic It is seldom documented if body alterations and neurotrophic factors in the body influence peripheral nerve regeneration following craniocerebral damage. Many factors, such as ethics, influence the pace with which nerves heal in clinical studies. Based on the above analysis, important influencing variables may be studied in order to enhance the repair effect of peripheral nerve damage, and successful modification of these influencing factors can improve the recovery effect of peripheral nerve injury

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