Analysis of hemodynamics and oxygenation in patients with hyoxemia caused by severe pulmonary infection treated by pulmonary reexpansion in the prone position

Abstract

Objective To study the application effect of pulmonary reexpansion in the prone position in patients with hyoxemia caused by severe pulmonary infection. Methods 75 cases of hyoxemia caused by severe pulmonary infection in our hospital from April 2013 to April 2015 were randomly divided into two groups. 45 patients in the observation group were treated by pulmonary reexpansion in the prone position, while 30 patients in the control group were treated by pulmonary reexpansion in the supine position. The changes of basic indexes, hemodynamics, and oxygenation indexes of the two groups were detected before and after pulmonary reexpansion, and the incidences of adverse reactions of the two groups were compared and analyzed. Results The vital signs of patients in the two groups had no statistically significant differences before pulmonary reexpansion (P>0.05); after pulmonary reexpansion, heart rate (HR) and mean arterial pressure (MAP) levels decreased in both two groups, but without statistically significant differences compared with those before pulmonary reexpansion (P>0.05); after pulmonary reexpansion, oxygen saturation (SpO2) and oxygen synthetic index (PaO2 / FiO2) levels significantly increased in both two groups (P 0.05); after pulmonary reexpansion, central venous pressure (CVP), stroke volume index (SVI) and global ejection fraction (GEF) levels significantly decreased in both two groups, systemic vascular resistance index (SVRI) significantly increased (P<0.05). The incidence of adverse reactions after pulmonary reexpansion was 4.44% in the observation group and 17.78% in the control group, with statistically significant difference between the two groups (χ2=4.936 3, P=0.044 2). Conclusion Pulmonary reexpansion in the prone and supine position both can significantly improve blood oxygenation and hemodynamic status in patients, but the therapeutic effect and safety of pulmonary reexpansion in the prone position are higher. Key words: Severe pulmonary infection; Hypoxemia; Pulmonary reexpansion; Prone position; Hemodynamics