Abstract

We analyzed the feedback relationship between short-term fluctuations in heart rate and blood pressure in healthy persons and heart failure patients. Parameters derived from the feedback relationship between heart rate and blood pressure have been proposed. The purpose of the present study is to apply these parameters in estimating autonomic function or measuring physiological and mental workload.Electrocardiographs and beat-to-beat blood pressure were recorded in supine position at rest. The blood pressure was measured using arterial tonometry. The R—R interval and systolic blood pressure were fitted to two-dimensional autoregressive models, the relative power contribution in the frequency domain was calculated. The proposed parameters are the power contribution in the low-frequency range ( 0-0.15 Hz ) [ RS_LF, SR_LF ] and the power contribution in the high-frequency range ( 0.15-0.5 Hz ) [ RS_HF, SR_HF ].RS_LF was significantly different between healthy persons and heart failure patients ( pThere were no correlations between the proposed parameters and the usual indices to evaluate autonomic function. It is considered that the proposed parameters can be used to evaluate physiological states that cannot be evaluated using existing methods.

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