Abstract
An attempt is made to analyse the haemoperfusion system. The patient's body is modelled as a 3-compartment system and the adsorber unit (perfusion system) is modelled as a 2-phase system with axial dispersion accounting for both the inter-particle and the intra-particle mass-transfer resistances. Results indicate that although the clearance of solute increases with an increasing blood-flow rate through the adsorber unit, the increase in clearance is not significant. The particle size (intra-particle mass-transfer resistance) and the volume of the adsorbent have a significant effect on the clearance of the solute.
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