Abstract
Objective: The natural history and progression of acute aortic syndrome (AAS) has been suggested to be more severe in patients with a familial history or a syndromic AAS.1 One of these being aortic dissection, in which the underlying aetiology is autosomal dominant gene variants in the heritable thoracic aortic disease (HTAD) genes. In New Zealand, large ethnic disparities in the presentation and incidence for patients presenting with AAS have been documented.2 Despite the underlying risk factors, the present authors postulate that there may be an increased genetic predisposition in select patient cohorts. The aim of this study was to analyse genetic variances in patients presenting with AAS.
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