Abstract
Fluoxetine hydrochloride, better known for its commercial name Prozac, is one of the most widely prescribed antidepressant drugs all over the world. This drug was considered a “breakthrough drug” for the treatment of depression because of its very high selectivity as a serotonin reuptake inhibitor and because it presented a lower side-effect profile than previous drugs (Wong et al., 2005). However, the precise mechanisms of fluoxetine action and how it alleviates mood disorders is still largely unknown.
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