Abstract
Objective To investigate the related factors of skin damage caused by peripherally inserted central catheter (PICC) in cancer patients. Methods It was a retrospective analysis of 202 cancer patients admitted to our hospital from February 2014 to July 2019. 50 cases of PICC-related skin damage and 152 cases of non-skin damage were studied. In addition, multivariate logistic regression analysis was used to determine independent risk factors for PICC-related skin damage, including cancer patients with catheter-related skin damage and patients without skin damage. Results 50 patients with PICC skin damage (19 males and 31 females) and 152 patients without skin damage (62 males and 90 females) were retrospectively analyzed. The skin damage rate was 24.8%. The analysis of variance results showed that many factors are related to PICC catheter-related skin damage, including hormones (χ2/Z = 4.468, P < 0.05), body mass index (BMI) (χ2/Z = −2.443, P < 0.05), days with tube (χ2 = 26.230, P < 0.05), chemotherapy cycle (χ2/Z = 25.638, P < 0.05), and self-care ability (χ2/Z = −1.968, P < 0.05). Logistic regression analysis showed that hormones (odds ratio (OR) = 3.896, P=0.045), BMI (OR = 1.129, P=0.017), days with tube (OR = 0.419, P=0.013), and chemotherapy cycle (OR = 3.302, P=0.028) are independent factors affecting PICC-related skin damage. Conclusion The independent influencing factors of skin damage during PICC catheterization are hormones, BMI, number of days with tube, and chemotherapy cycle.
Highlights
Inserted central catheters (PICCs) are vascular access devices [1], which have the advantages of simple operation, safety, and long catheter indwelling time [2]
A total of 202 patients with peripherally inserted central catheter (PICC)-related skin damage were included, including 81 males and 121 females. e incidence of PICCrelated skin damage was 24.75%, of which men accounted for 23.5% and women accounted for 25.6%. e analysis results show that, whether or not to use hormones, the number of days with tube, body mass index (BMI), self-care ability, and the chemotherapy cycle are statistically significant in comparing whether there is skin damage during PICC catheterization (P < 0.05); see Table 1
Taking whether the patient had skin damage as the dependent variable, and whether using hormones, the number of days with tube, BMI, self-care ability, and chemotherapy cycle as independent variables, a binary logistic regression analysis was performed. e variable assignment is shown in Table 2. e results show that hormone use, number of days with tube, BMI, and chemotherapy cycle are the influencing factors for skin damage during PICC catheterization; see Table 3. e results show that hormone use is most closely related to PICC-related skin damage, followed by chemotherapy cycles, BMI, and days with tube
Summary
Inserted central catheters (PICCs) are vascular access devices [1], which have the advantages of simple operation, safety, and long catheter indwelling time [2]. PICC provides a lot of convenience to patients and medical staff [3], the occurrence of complications will weaken these advantages. Skin damage is a common complication associated with PICC [4]. Long-term indwelling PICC catheters in some patients are prone to iatrogenic skin damage, which increases patient suffering and even affects clinical treatment, which is not conducive to recovery [6]. E length of the catheterization time, the patient’s physique, the chemotherapy cycle, the use of hormones, and other factors can cause skin allergies, eczema, and other problems to general patients [7, 8]. The skin irritation affects the daily life of the patient, and in the worst case, it may aggravate the complications such as early extubation and skin redamage, affecting the life of PICC and increasing the economic burden of patients [9]
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