Abstract
Abstract A new antidiabetic agent, N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine (A4166), and its L-enantiomer were successfully separated and quantified by high-performanece liquid chromatograph. This direct resolution was accomplished using a chiral stationary phase column packed with 5 μm N-(tert-butylaminocarbonyl)-L-valylaminopropyl silica gel and a mobile phase consisting of n-hexane/n-propanol/trifluoroacetic acid. The method has been used for the analysis of plasma samples from beagle dogs.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
