Analysis of dosimetric properties in the field of radiotherapy of glucose irradiated by megavoltage X photons, electrons and analyzed by EPR spectroscopy

Abstract

Abstract In this work, we propose to analyze the dosimetric properties of the glucose Electron Paramagnetic Resonance (EPR) system. This study consists of irradiating samples of glucose by megavoltage X photons and electrons delivered by a particle accelerator used in radiotherapy. After irradiation, the samples were analyzed by EPR. The measurements obtained on samples placed at different depth in a phantom of PolyMethyl Methacrylate “PMMA” have firstly identified the depths corresponding to the maximum dose deposition for both particles and samples used. Analysis by EPR showed that the threshold measurable dose for this dosimetric system is about 2 Gy. The variation of curves obtained from the peak-to-peak EPR intensity, or the results of the double integration of the spectrum as a function of the irradiation dose, are linear with a correlation coefficient exceeding 0,999. Glucose seems slightly more sensitive to megavoltage X photons than megavoltage electrons. The results reveal interesting potential dosimetry of the glucose/EPR system in the field of radiation therapy.