Abstract
Objective To analyze the distribution and drug resistance of Acinetobacter baumannii infection in neurosurgical care unit, and to provide basis for rational control of nosocomial infection and use of antibiotics. Methods The infection distribution and drug resistance of 150 Acinetobacter baumannii strains isolated from blood, sputum, cerebrospinal fluid and surgical wound sites in the neurosurgical care unit of the 11th Clinical College of Shanxi Medical University from January 2018 to December 2020 were analyzed retrospectively. Results The infection rate of Acinetobacter baumannii was 74.16% in respiratory tract, 15.00% in intracranial and 13.40% in surgical wound in the neurosurgical care unit. The drug resistance rate of Acinetobacter baumannii to amtronem was the highest (90.00%), followed by piperacillin (88.10%), polymyxin E was the lowest (2.38%), followed by ampicillin/sulbactam (57.14%). Conclusion Acinetobacter baumannii infection is mainly distributed in the lower respiratory tract, intracranial and surgical wounds in neurosurgical care units, and the drug resistance rate of Acinetobacter baumannii to aminotronem and piperacillin is high. Clinical application of antibiotics should be rational, and the types and doses of antibiotics need to be adjusted dynamically in order to further strengthen the control of nosocomial infection.
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