Abstract

Tuberculosis is classified as a chronic respiratory disease with its pathogen being Mycobacterium tuberculosis (MTB). It poses a significant health threat due to its highly contagious nature and is difficulty in treatment. Various methods are employed to test for tuberculosis, including pathological, immunological and molecular biological tests. Each test has its unique principles and all are different in effects, and are widely used in clinical practice. In this research, principles, development and effects of each type of tests in testing pulmonary tuberculosis will be explored respectively. Additionally, the review will provide insights into the optimization of tuberculosis testing by comparing and contrasting different testing methods. Pathological tests represent the most traditional approach to testing for tuberculosis. Bacterial culture, a pathological test, is the gold standard of tuberculosis test. Nevertheless, it suffers from a long detection time. Meanwhile, immunological tests and molecular biological tests benefits from a fast detection, while the accuracy of the tests can be influenced by multiple factors. Thus, it will accelerate the detection speed while enhancing the precision to combine three different kinds of tests in clinical practice.

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