Abstract
Objective: The aim of the study is to investigate the detection rate of early evening elevated blood pressure (EEE) in treated and untreated hypertensive patients by ambulatory blood pressure monitoring. Design and method: From February 1, 2020 to February 28, 2023, the total of 1413 hypertensive patients underwent ambulatory blood pressure monitoring in 13 medical institutions through the National 13th Five Year Plan Major Cooperation Group for Chronic Disease Prevention and Control (Research on the Application of Lifestyle and Nutritional Intervention Techniques and Strategies for Obesity and Hypertension, No. 2016YFC1300100). Among them, 1026 patients had taken antihypertensive drugs and 387 patients had not taken antihypertensive drugs. EEE is defined as average systolic blood pressure is higher or equal to 135mmHg or average diastolic blood pressure is higher or equal to 85mmHg from 6PM to 10PM. Results: 1. The detection rate of EEE in treated hypertensive patients was 60.4% (620 patients), while the detection rate of EEE in untreated hypertensive patients was 70.5% (273 patients); 2. The detection rate of daytime hypertension in treated hypertensive patients was 55.8% (573 patients), while the detection rate of daytime hypertension in untreated hypertensive patients was 71.6% (277 patients); 3. The detection rate of nighttime hypertension in treated hypertensive patients was 81.2% (833 patients), while the detection rate of nighttime hypertension in untreated hypertensive patients was 87.6% (339 patients); 4. The detection rate of whole-day hypertension in treated hypertensive patients was 69.3% (711 patients), while the detection rate of whole-day hypertension in untreated hypertensive patients was 80.9% (313 patients); 5. The detection rate of morning hypertension in treated hypertensive patients was 61.1% (627 patients), while the detection rate of morning hypertension in untreated hypertensive patients was 72.9% (282 patients). Conclusions: In this study, the detection rate of EEE in treated hypertensive patients did not significantly decrease compared to those untreated patients, while the detection rate of EEE was similar to that of morning hypertension. It is necessary to conduct further research to reveal the correlation between EEE and cardiovascular diseases.
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