Abstract

To study puff-by-puff release characteristics of crotonaldehyde in mainstream cigarette smoke under diverse intensive smoking regimens, we designed an RM20H smoking machine with a puff-by-puff smoke collection unit to automatically trap crotonaldehyde in the mainstream cigarette smoke. Using this process, we trapped, puff-by-puff, crotonaldehyde in mainstream smoke generated by different smoking regimens and quantitatively analysed the levels of crotonaldehyde using high-performance liquid chromatography with a modified QuEChERS sample pretreatment method. On the basis of the crotonaldehyde in each puff, we determined crotonaldehyde's puff-by-puff release characteristics. The results showed that crotonaldehyde's puff-by-puff release remained nearly constant for the International Organization for Standardization mode while increased polynomial trend was seen (n ≥ 6) under the Massachusetts and Health Canada smoking regimens. The equation fit for various regimens was good (R2 > 0.9192). Release characteristics by puff were classified into four categories: (1) first, second and third puffs; (2) fourth and fifth puffs; (3) sixth puff; and (4) seventh and eighth puffs.

Highlights

  • Cigarette smoking machines are used to simulate consumer smoking behaviour, which is important for the study of the chemical composition of mainstream cigarette smoke

  • The results showed that crotonaldehyde’s puff-by-puff release remained nearly constant for the International Organization for Standardization mode while increased polynomial trend was seen (n ≥ 6) under the Massachusetts and Health Canada smoking regimens

  • As debate on the relevance of the International Organization for Standardization (ISO) smoking parameters continues in the literature, it is important to study the effect of smoking regimens on chemical release because it affects the combustion of cigarettes [3]

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Summary

Introduction

Cigarette smoking machines are used to simulate consumer smoking behaviour, which is important for the study of the chemical composition of mainstream cigarette smoke. As debate on the relevance of the ISO smoking parameters continues in the literature, it is important to study the effect of smoking regimens on chemical release because it affects the combustion of cigarettes [3]. Study of the effects of different smoking regimens (including the Massachusetts and Health Canada intensive smoking regimens) on puff-by-puff chemical composition in cigarette mainstream smoke has an increasingly important role in the accurate analysis of smoke emission [4]. Li and coworkers [14] studied the release of six chemical constituents by puff in ISO mode using a transformation smoking machine. Chen [15] studied the relationship between important parameters and the release of crotonaldehyde in mainstream smoke by changing key process parameters in the method

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