Abstract
The aim of the present study was to evaluate the association between computed tomography (CT) images and the pathological observations of non-Hodgkin lymphoma (NHL) patients with peritoneal, omental and mesenteric involvement. In total, 26 patients suffering from an NHL with peritoneal, omental or mesenteric involvement were reviewed retrospectively, and the observed CT scan characteristics were analyzed. In addition, associations among the CT scan characteristics and the NHL subtypes, including diffuse large B-cell, mantle cell, follicular cell and T-cell lymphoma, were evaluated. The CT scan characteristics of the NHLs with peritoneal, omental and mesenteric involvement included peritoneal cord-like thickening, peritoneal omental nodular and swelling thickening, omental cake-like thickening and mesenteric mass. The probability of peritoneal linear, omental nodular and swelling thickening was found to be higher in diffuse large B-cell lymphoma cases compared with cases of other NHL subtypes (P<0.05). However, the probability of omental cake-like thickening and mesenteric mass was not found to be significantly different among the NHL subtypes (P>0.05). Signs of peritoneal, omental and mesenteric involvement were observed in the CT scans of all the NHL subtypes, particularly in diffuse large B-cell lymphoma cases. Therefore, linear, omental nodular and swelling thickening were characteristic of diffuse large B-cell lymphoma, while omental cake-like thickening and mesenteric mass were observed in all NHL subtypes.
Highlights
Lymphomas are a group of malignancies that occur in the lymph nodes, extranodal lymphoid tissues and the monocyte‐macrophage cell system [1]
It is rare that non‐Hodgkin lymphoma (NHL) invades the peritoneum, omentum or mesentery, lymphoma is considered in the differential diagnosis of extensive peritoneal tumor lesions in computed tomography (CT) images, as the treatment and prognosis differs compared with other types of tumor and the method can improve current understanding of CT signs of the disease
Diffuse large B‐cell lymphomas were most commonly diagnosed in NHL patients with peritoneal, omental or mesenteric involvement, while the number of these patients diagnosed with the other three subtypes was significantly lower (Table I)
Summary
Lymphomas are a group of malignancies that occur in the lymph nodes, extranodal lymphoid tissues and the monocyte‐macrophage cell system [1]. According to the cell source, NHLs are divided into B‐cell and natural killer/T‐cell types, while B‐cell NHLs can be divided into further subtypes, including diffuse large B‐cell, mantle cell and follicular lymphomas [2]. NHLs involving the omentum are not commonly observed in autopsies, but are more common in diffuse large B‐cell, mantle cell, follicular cell and T‐cell lymphomas [6]. It is rare that NHL invades the peritoneum, omentum or mesentery, lymphoma is considered in the differential diagnosis of extensive peritoneal tumor lesions in computed tomography (CT) images, as the treatment and prognosis differs compared with other types of tumor and the method can improve current understanding of CT signs of the disease. The aim of the present study was to investigate the correlation between CT images and pathological observations of NHLs with omental, peritoneal or mesenteric involvement
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