ANALYSIS OF CLINICAL, RADIOGRAPHIC, AND HISTOLOGICAL CHARACTERISTICS OF AN ADENOMATOID ODONTOGENIC TUMOR

Abstract

Objective This study aimed to evaluate the clinical, radiographic, and histopathological characteristics of 20 cases of AOT. Study Design Clinical and radiographic data were collected from the patients’ files, recorded over a 17-year period. Age, sex, race, location, size, duration of the lesion, AOT variant, radiographic aspects of density, locularity and edges, and detailed histopathological features were analyzed. Results Sixteen patients (80.0%) were female and 4 (20.0%) were male, with a mean age of 22.7 years. All lesions were intraosseous and affected the maxilla (70.0%) and mandible (30.0%), with a mean size of 39.4 mm and a mean injury duration of 14.8 months. Twelve tumors (85.7%) were follicular and 3 (14.3%) were extrafollicular. Five patients presented pain (31.3%). Microscopically, 12 cases showed a predominantly solid pattern (60.0%), three predominantly cystic (15.0%), and five (25.0%) without predominance. Classic histological patterns were identified in the following proportion in the cases: solid nodules (95.0%), lace-like cords (90.0%), rosettes (90.0%), duct-like structures (90.0%) and areas of mineralization (80.0%). Conclusion Clinical, radiographic, and histopathological characteristics in this case series from Brazil are similar to findings in other populations. This study aimed to evaluate the clinical, radiographic, and histopathological characteristics of 20 cases of AOT. Clinical and radiographic data were collected from the patients’ files, recorded over a 17-year period. Age, sex, race, location, size, duration of the lesion, AOT variant, radiographic aspects of density, locularity and edges, and detailed histopathological features were analyzed. Sixteen patients (80.0%) were female and 4 (20.0%) were male, with a mean age of 22.7 years. All lesions were intraosseous and affected the maxilla (70.0%) and mandible (30.0%), with a mean size of 39.4 mm and a mean injury duration of 14.8 months. Twelve tumors (85.7%) were follicular and 3 (14.3%) were extrafollicular. Five patients presented pain (31.3%). Microscopically, 12 cases showed a predominantly solid pattern (60.0%), three predominantly cystic (15.0%), and five (25.0%) without predominance. Classic histological patterns were identified in the following proportion in the cases: solid nodules (95.0%), lace-like cords (90.0%), rosettes (90.0%), duct-like structures (90.0%) and areas of mineralization (80.0%). Clinical, radiographic, and histopathological characteristics in this case series from Brazil are similar to findings in other populations.