Analysis of clinical presentation, biochemical profile, and management of liver abscess in North India

Abstract

<br><b>Objectives:</b> Liver abscess is a common disease in tropics with high morbidity and mortality if left untreated. It is quite prevalent among low socioeconomic population. In this study, we have analyzed the clinical and biochemical profile with management options for cases of liver abscess presented at a tertiary care hospital of Northern India.<br><b>Materials and Methods:</b> This was an observational prospective study conducted at Santosh Medical College and Hospital from March 2019 to March 2021. All patients underwent extensive clinical, biochemical evaluation and radiological examination, followed by treatment as per reports and requirement. All results were formulated in tabular form and analyzed accordingly.<br><b>Results:</b> Liver abscess is commonly seen in the Indian subcontinent. Middle-aged males are predominantly affected. Alcohol intake and diabetes are the significant risk factors. Pain abdomen and fever were the most frequent complaints. <i>Escherichia coli</i> was the most common organism causing pyogenic liver abscess. More than 75% of the cases can be treated with antibiotics and ultrasound-guided single needle aspiration.<br><b>Conclusion:</b> Hepatic abscess is a common disease of Indian subcontinent. Early diagnosis and treatment is essential to prevent mortality. Ultrasound has emerged as a cheaper and effective diagnostic modality. The incidence of tubercular hepatic abscess is not uncommon.<br>