Analysis of clinical features and prognostic correlation factors of sudden sensorineural hearing loss in children.

Abstract

This study aimed to investigate the clinical features and prognostic correlation factors of sudden sensorineural hearing loss in children (CSSNHL). From January 2016 to December 2021, the clinical data of hospitalized children presenting with sudden sensorineural hearing loss, including age, gender, the ear of onset, onset of treatment, concomitant symptoms, the degree of hearing loss, and audiogram curve type, were retrospectively collected and the effective rate of treatment and the factors affecting prognosis were statistically analyzed. The effective rate of CSSNHL was 29.97%. Univariate analyses showed that the onset of treatment, the degree of hearing loss, audiogram curve type, and tinnitus were associated with prognosis (P<0.05). Multivariate analyses showed that onset of treatment was correlated with prognosis (OR=0.939, 95% CI=0.911-0.969, P<0.001). Compared with patients in the profound group, the therapeutic performance of the severe, moderate, and mild groups were significantly different (OR=9.951, 11.264, 13.373, 95% CI=2.311-42.856, 2.818-45.028, and 5.310-33.677, P<0.05). Compared with patients with profound audiogram, ascending audiogram and flat audiogram were related to therapeutic performance (OR=13.373 and 14.481, 95% CI=5.310-33.677, 6.509-32.217, P<0.001). The prognosis of CSSNHL patients was related to the onset of treatment, the degree of hearing loss, and the audiogram curve type. Patients who received earlier treatment, had lighter hearing loss and the ascending and flat audiograms exhibited improved prognosis.