Analysis of Clinical Characteristics and Blood Cell in Adult Patients with Brucella Bloodstream Infection of Different Blood Groups.

Abstract

The clinical manifestations and blood cell varied among patients with Brucella bloodstream infection. This study aimed to explore the clinical characteristics and blood cells of adult Brucella bloodstream infection patients with different ABO blood groups. This study retrospectively analyzed 77 adult Brucella bloodstream infection patients. Demographic characteristics, clinical manifestations, laboratory data, and blood cell differences of adult Brucella bloodstream infection patients were analyzed. For Brucella bloodstream infection patients, the blood group was distributed as: B > O > A > AB. The main symptoms of the patients were fever (94.81%), and 56 patients (72.70%) were complicated with liver injury. The highest proportion of liver injury was 93.33% in patients with blood group A and 52.38% in blood group O (P < 0.05). There were 19 cases (24.68%) with spondylitis, 30 cases (38.96%) with anemia, 28 (36.36%) with leukopenia, 16 (20.78%) with thrombocytopenia, without notable differences between different blood groups (P > 0.05). The proportion of lymphocytes in patients with the AB blood group was the highest (39.46 ± 11.21), and in patients with the B blood group was the lowest (28.00 ± 12.10), with significant difference between different blood groups (P < 0.05). Patients with Brucella bloodstream infection with blood group A were more prone to liver injury than those with blood group O. More attention should be paid to liver injury when receiving patients with blood group A. The proportion of lymphocytes in patients with blood group B and AB was different, suggesting that they may have different immune states.