Abstract
Materials/Methods: Clinical results were analyzed retrospectively for 241 NSCLC patients treated with concurrent chemotherapy and definitive 3D-CRT during 1999–2003 at our center. Acute esophagitis was assessed using CTC 2.0 criteria. Dose distributions and DVHs of esophagus were calculated from 3DCRT treatment plans according to physical dose and biological equivalent dose (2Gy/fraction). Univariate logistic analyses were performed to evaluate the risk of grade-3 and above acute esophagitis among the following clinical factors: gender, age, KPS, cardiovascular disease, tumor location, N-stage, clinical stage, prescription dose, fraction per day, induction chemotherapy and agents. Dosimetrical factors analyzed were: relative and absolute esophagus volume treated above certain doses, and mean dose and total volume of esophagus. Factors with statistical significance in the univariate analysis were included in the subsequent multivariate analysis with forward step-wise inclusion of variables.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Radiation Oncology*Biology*Physics
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
