Abstract
BackgroundThe main purpose was to determine basic epidemiological data on CKD among hospitalized pediatric patients in China.MethodsData from pediatric inpatients with CKD hospitalized from June 1, 2013 to May 31, 2017 were extracted from the electronic records of HQMS database, which includes over 14 million inpatients. Codes from the 10th revision of the International Classification of Diseases (ICD-10) were used to search the database.ResultsA total of 524 primary diseases of CKD were included in this study. In all, there were 278 231 pediatric inpatients with CKD, which accounted for 1.95 % of the 14 250 594 pediatric inpatients registered in the HQMS database. The number of pediatric inpatients with CKD was 67 498 in 2013, 76 810 in 2014, 81 665 in 2015 and 82 649 in 2016, which accounted for 1.93 %, 1.93 %, 1.99 and 2.09 %, respectively, of the total population of pediatric inpatients. The etiology of CKD was secondary nephrosis in 37.95 % of cases, which ranked first and followed by CAKUT with a percentage of 24.61 %. Glomerular diseases and cystic kidney disease accounted for 21.18 and 5.07 %, respectively. Among all 278 231 patients, 6 581 (2.37 %) had a primary discharge diagnosis of CKD. The renal pathology findings of CKD showed that IgA accounted for 51.17 %.ConclusionsThis study provides a descriptive analysis of the hospitalized population of pediatric CKD patients. Our study provides important, fundamental data for policy making and legislation, registry implementation and the diagnosis, treatment and prevention of CKD in China.
Highlights
The main purpose was to determine basic epidemiological data on Chronic kidney disease (CKD) among hospitalized pediatric patients in China
The epidemiology of childhood end-stage renal disease (ESRD) has been analyzed in the USA, Europe, Australia and New Zealand [8]; these data represent only part of the pediatric population with CKD, because many children with renal impairment will not develop ESRD until adulthood [9]
No nationwide epidemiological data on childhood CKD have been reported; the only nationwide study was conducted by the Chinese Society of Pediatric Nephrology and focused on chronic renal failure (CRF), not CKD, in 91 hospitals in China in 2004 [10]
Summary
The main purpose was to determine basic epidemiological data on CKD among hospitalized pediatric patients in China. The epidemiology of childhood ESRD has been analyzed in the USA, Europe, Australia and New Zealand [8]; these data represent only part of the pediatric population with CKD, because many children with renal impairment will not develop ESRD until adulthood [9]. There is a paucity of data on the epidemiology of CKD in children worldwide, especially in developing countries like China [6]. No nationwide epidemiological data on childhood CKD have been reported; the only nationwide study was conducted by the Chinese Society of Pediatric Nephrology and focused on chronic renal failure (CRF), not CKD, in 91 hospitals in China in 2004 [10]. Over 9 % of patients with stage 3 or 4 CKD progress to ESRD [11]
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