Abstract
目的 研究肝移植术后期的死亡率和主要死亡原因, 探讨肝移植术后期导致死亡的主要并发症的风险因素、预防和治疗.方法回顾性地研究1981年2月至1998年4月进行的生存期大于1年的2940例肝移植长期随访结果, 着重分析其主要死亡原因与相关因素.结果肝移植术后第1~10年死亡率依次为20.4%,6.7%,4.5%,3.8%,3.7%、4.6%,3.5%,3.3%,2.9%,1.9%.后期死亡817例,主要原因依次为恶性肿瘤(复发+新生;20.69%)、心血管并发症(11.38%)、各种感染(11.26%)和呼吸系统并发症(9.42%).结论肝移植术后期主要死亡原因为复发或新生恶性肿瘤、心血管并发症、各种感染和呼吸系统并发症.尽早预防和及时治疗这些并发症,成为进一步提高肝移植长期生存率的关键。
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