Analysis of breast calcification and pathological types of breast lesions

Abstract

Objective To ananlyze the correlation between calcification features and histopathological characteristics of benign and malignant lesions proved by surgical biopsy after digital mammography-guided wire locailzation of microcalcification in breast. Methods Retrospectively analyzed the microcalcification in FFDM examination and guided localization biopsy of 206 patients of breast calcify pathology morphology and the correlation between the positioning and histopathological characteristics. Results The differences of breast calcifications morphology and positioning between the benign and malignant lesions had significanty difference (P<0.05), calcification characteristics between benign lesions or malignant lesions had no significant difference. Conclusions The calcification pathological morphology, number and position, as well as its correlation with surrounding structures are effective signs of differentiating malignant breast calcifications from benign ones. Key words: Mammography; Microcalcification; Histopathology; Wire locailzation biopsy