Analysis of Blood Urea-Nitrogen to Creatainine (BUN/CR) Ratio at Different Stages of Chronic Kidney Disease in Baiturahim Hospital Jambi

Abstract

Background: Renal failure is a disease in which the function of the kidneys decreases until they are no longer able to work at all in terms of filtering the body's electrolyte disposal, maintaining the balance of fluids and body chemicals such as sodium and potassium in the blood or urine production. Decreased kidney function indicates an increase in creatinine and urea levels in the blood. GFR or the ability of the kidneys to filter blood can be assessed by measuring serum creatinine levels, blood urea nitrogen levels. Serum blood urea nitrogen (BUN) levels are inversely proportional to GFR. The normal BUN/Creatinine ratio is 10-15:1. The aim of this study was to determine the difference in the average BUN/Creatinine ratio in patients with Chronic Kidney Failure and Stage V Kidney Failure patients undergoing routine hemodialysis.
 Method: This research is a quantitative descriptive study by taking secondary data from medical record data on 70 patients treated at Baiturrahim Hospital Jambi for the period February 2022-February 2023. Variables assessed in this study include the severity of kidney failure with the results of urea and creatinine examinations.
 Result: Based on research that has been carried out found that the average BUN/Creatinine ratio in patients at non-end stage of CKD was 11.97, while in ESRD patients it was 5.69.
 Conclusion: There was a significant difference between the results of the BUN/Creatinine ratio in patients with Chronic Kidney Failure and ESRD (P-value < 0.01) at Baiturrahim Hospital Jambi.