Abstract
BackgroundOur long-term goal is to design and manufacture a customized graft with porous scaffold structure for repairing large mandibular defects using topological optimization and 3D printing technology. The purpose of this study is to characterize the mechanical behavior of 3D printed anisotropic scaffolds as bone analogs by fused deposition modeling (FDM).MethodsCone beam computed tomography (CBCT) images were used to reconstruct a 3D mandible and finite element models. A virtual sectioned-block of the mandible was used as the control group and the trabecular portion of the block was modified by topological optimization methods as experimental groups. FDM (FDM) printed samples at 0, 45 and 90 degrees with Poly-lactic acid (PLA) material under a three-point bending test. Finite element analysis was also used to validate the data obtained from the physical model tests.ResultsThe ultimate load, yield load, failure deflection, yield deflection, stress, strain distribution, and porosity of scaffold structures were compared. The results show that the topological optimized graft had the best mechanical properties.ConclusionsThe results from mechanical tests on physical models and numerical simulations from this study show a great potential for topological optimization and 3D printing technology to be served in design and rapidly manufacturing of artificial porous grafts.
Highlights
Autograft and allograft are commonly used for bone grafting procedures to repair segmental bony defects, which usually result from trauma, infection and tumor resection of tumors [1,2,3]
Our long-term goal is to develop a new method to overcome the drawbacks of traditional bone grafting procedures for treating segmental bony defects by using 3D printing technology. 3D virtual mandibular grafts were designed based on cone beam computed tomography (CBCT) images and subsequently fabricated by 3D fused deposition modeling (FDM) printing for reconstruction of a patient-specific mandibular defect
Maximum von Mises stress, principal strain, and displacement were calculated from finite element analysis using numerical simulation models
Summary
Autograft and allograft are commonly used for bone grafting procedures to repair segmental bony defects, which usually result from trauma, infection and tumor resection of tumors [1,2,3]. Our long-term goal is to develop a new method to overcome the drawbacks of traditional bone grafting procedures for treating segmental bony defects by using 3D printing technology. The biodegradation behavior is a critical characteristic of the materials and the most important reason for the high interest in its use in medical applications and industry. It begins to decompose into lactic acid (LA), carbon dioxide and water once in contact with biological media. Our long-term goal is to design and manufacture a customized graft with porous scaffold structure for repairing large mandibular defects using topological optimization and 3D printing technology. The purpose of this study is to characterize the mechanical behavior of 3D printed anisotropic scaffolds as bone analogs by fused deposition modeling (FDM)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
