Abstract
Partial breast irradiation (PBI) is currently being investigated as an alternative to conventional whole breast irradiation (WBI). The benefits of PBI compared to WBI include a shorter treatment time and possible reduction in dose to normal tissue. However, the biological effects of hypofractionation must also be considered for normal tissues treated with PBI. The purpose of this study was to examine radiation dose to lung tissue for 3 dimensional (3-D) conformal external beam partial breast irradiation (PBI) and standard whole breast irradiation (WBI). Biologically equivalent dose (BED) was used to account for the altered dose and fractionation of PBI.
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