Abstract
Commercial products labeled as grapefruit seed extract (GSE) are promoted as natural antimicrobial agents for both internal and external use. A simple, precise and more sensitive UHPLC analytical method is presented for the simultaneous detection and quantitation of three preservatives namely methyl paraben (1), benzethonium chloride (2), and triclosan (3) in various commercial Grapefruit seed/grape seed/pomegranate seed samples. Compound identity was further confirmed by electrospray ionization mass spectrometry (HRESI-MS). The main constituent identified was benzethonium chloride, a synthetic antimicrobial agent which was found in 5 samples. Positive ion electrospray MS of the commercial GSE sample showed a molecular ion at m/z 412 [M+] that matched with that of a standard of benzethonium chloride. Triclosan detected in three samples and methyl paraben was not detected in all the samples analyzed.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
