Analysis of articular cartilage as a composite using nonlinear membrane elements for collagen fibrils

Abstract

To develop a composite fibre-reinforced model of the cartilage, membrane shell elements were introduced to represent collagen fibrils reinforcing the isotropic porous solid matrix filled with fluid. Nonlinear stress–strain curve of pure collagen fibres and collagen volume fraction were explicitly presented in the formulation of these membrane elements. In this composite model, in accordance with tissue structure, the matrix and fibril membrane network experienced dissimilar stresses despite identical strains in the fibre directions. Different unconfined compression and indentation case studies were performed to determine the distinct role of membrane collagen fibrils in nonlinear poroelastic mechanics of articular cartilage. The importance of nonlinear fibril membrane elements in the tissue relaxation response as well as in temporal and spatial variations of pore pressure and solid matrix stresses was demonstrated. By individual adjustments of the collagen volume fraction and collagen mechanical properties, the model allows for the simulation of alterations in the fibril network structure of the tissue towards modelling damage processes or repair attempts. The current model, which is based on a physiological description of the tissue structure, is promising in improvement of our understanding of the cartilage pathomechanics.