Analysis of apoB, HLADQ alpha, and D1S80 polymorphisms in the Italian population using the polymerase chain reaction.

Abstract

Allele and genotype frequencies of three highly polymorphic loci (apoB, HLADQ alpha, D1S80) have been determined in an Italian sample using the polymerase chain reaction (PCR) amplification and non-radioactive detection. The allele frequencies ranged from 0.1% to 39%, with an average heterozygosity of 0.74 and a power of discrimination ranging from 0.90 to 0.98. These results are of value for forensic and genetic studies. © 1992 Wiley-Liss, Inc.