Abstract

The world is suffering through large number of diseases which are primarily caused by the microbes, though it is bacteria, fungi, viruses or protozoans. The inappropriate, prolonged use of antibiotics and loss of biodiversity and climate change is leading to the invasion of microbes in the human population, because of which every individual on the earth is suffering from diseases caused by microorganisms. In current scenario it is the prerequisite to screen the effective, safe, cheap, and available therapeutics from plants and natural products. Plant parts of sixteen medicinal plant species such as Aegle marmelos, Allium cepa, Allium sativum, Azadirachta indica, Calotropis procera, Cassia fistula, Catharanths roseus, Coriandrum sativum, Curcuma longa, Emblica officinalis, Eucalyptus, Mentha piperita, Nerium oleander, Ocimum sanctum, Withania somnifera and Zingiber officinale with high antimicrobial activity against Gram-positive bacteria Bacillus subtilis, Gram-negative Escherichia coli and fungus Aspergillus niger were extracted with aqueous, ethanol and acetone and with the help of well diffusion method minimal inhibitory concentration (MIC) values were determined.
 Out of three solvent phases, ethanol extract showed the highest inhibition against the microbes, where as the efficacy of most of the aqueous and acetone plant extracts were also confirmed as antimicrobial agent and their use as therapeutic drugs for the treatment of various diseases.

Highlights

  • Medicinal herbology is a trend of modern life culture in global perspective

  • In view of vast application of natural herbs as antimicrobial agent, the main focus of this this study is to investigate in vitro antibacterial and antifungal activity of extracts from some selected medicinal plants and to find out the effective solvent phase of plant extracts

  • To determine the antimicrobial activity, nine sets were prepared for each plant extract, three for gram positive, three for gram negative bacteria and three for fungal strain in all the solvent phases used for different solvent distilled water, acetone and ethanol

Read more

Summary

INTRODUCTION

Medicinal herbology is a trend of modern life culture in global perspective. In current scenario everyone is facing health changes because of microbial agents. Through the knowledge people can treat themselves, against various alignments. About 80% people round the globe has been shifted towards the herbal medicines for their primary care of ailments. Treatment through the natural products or herbs are always considered safe and without side effects. A vast number of natural products are known as antimicrobial agents which helps to treat the infectious disease [1]. Secondary metabolites of the plants make them a potential source of antimicrobial agents [2,3]. In view of vast application of natural herbs as antimicrobial agent, the main focus of this this study is to investigate in vitro antibacterial and antifungal activity of extracts from some selected medicinal plants and to find out the effective solvent phase of plant extracts

MATERIALS AND METHODS
Microbial Cultures
Antimicrobial Assay of Plant Extracts
Preparation of Plant Extracts
RESULTS AND DISCUSSION
CONCLUSION
ETHICAL APPROVAL
Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call