Abstract

To evaluate prescription receipts for antimicrobial prescriptions prescribed in primary healthcare units in a capital city in the Northeast region of Brazil. An evaluative, analytical study. Information from the central distribution of essential medicines and the receipts of antimicrobial prescriptions were used. There were 2,232 prescription receipts analyzed, in which metronidazole (250 mg) was prescribed in 28% of the evaluated prescription receipts, the "pill" pharmaceutical form in 30.7%, and the "oral" administration form in 78.2%. In the prescriptions prescribed by nurses, 80.7% were intended for users with sexually transmitted infections. With the exception of the pharmaceutical form, only 34.7% of the prescriptions were in accordance with the Nursing protocol recommendations. There is still no information on the concentration (43.7%), the dosage (39.9%) and the treatment time (36.8%). The evaluated receipts of antimicrobial prescriptions do not accurately follow the guidelines of Resolution No. 20/2011, nor of the instituted Nursing protocol.

Highlights

  • The irrational prescription of antimicrobials in Primary Healthcare (PHC) has significantly contributed to the phenomenon of antimicrobial resistance (AMR), since the consumption of these drugs has considerably increased in the last decades in the community[1]

  • The seriousness of this situation in Brazil culminated in a stance by the National Health Surveillance Agency (ANVISA – Agência Nacional de Vigilância Sanitária) to issue Collegiate Board Resolution (RDC) no. 20/2011 with the aim of promoting actions to control antimicrobials in the context of PHC, which links the sale and dispensing of these medications to retaining special control prescription receipts in two copies[3]

  • This publication allows state governments to establish protocols within the scope of PHC, a movement followed by the Municipality of Teresina, Piauí state, which created the Nursing Protocol in Primary Care and Outpatient Services in 2012, being composed of 10 subprotocols in several areas and constituting the Ministry of Health Manuals and Portals as reference[5].This protocol issues local guidelines for nurses to prescribe antimicrobials within two subprotocols: Sexually Transmitted Infections (STI) and Child Health, being pointed out as an important strategy to streamline the care provided to these diseases in PHC

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Summary

Introduction

The irrational prescription of antimicrobials in Primary Healthcare (PHC) has significantly contributed to the phenomenon of antimicrobial resistance (AMR), since the consumption of these drugs has considerably increased in the last decades in the community[1]. 20/2011 with the aim of promoting actions to control antimicrobials in the context of PHC, which links the sale and dispensing of these medications to retaining special control prescription receipts in two copies (from the user and the health unit that dispensed the medication)(3) Following this trend, the Ministry of Health (MoH), supported by Law No 7.498, of June 25, 1986 (Law of Professional Nursing Practice), issued Ordinance No 2.488/2011 in the same year, which reaffirms prescription of specific medications within the PHC as a specific attribution of nurses, provided that it occurs according to “protocols or other technical regulations established by the Federal, State, Municipal or Federal District manager”(4). This publication allows state governments to establish protocols within the scope of PHC, a movement followed by the Municipality of Teresina, Piauí state, which created the Nursing Protocol in Primary Care and Outpatient Services in 2012, being composed of 10 subprotocols in several areas and constituting the Ministry of Health Manuals and Portals as reference[5].This protocol issues local guidelines for nurses to prescribe antimicrobials within two subprotocols: Sexually Transmitted Infections (STI) and Child Health, being pointed out as an important strategy to streamline the care provided to these diseases in PHC

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