Abstract
Objective To explore the adverse reactions of Infliximab and its relevant nursing countermeasures. Methods The clinical data from 13 patients were collected. Condition of adverse reaction was observed and nursing countermeasures were conducted. Results A total of 65 times of Infliximab-infusion were conducted in the 13 patients. Serum sickness reaction appeared 6 times, infection occurred 7 times and liver dysfunction occurred 2 times. According with those adverse reactions, nursing interventions including standard medication,infection prevention and observation were conducted. Conclusions The highest incidence of all adverse reactions is infection followed by serum sickness reaction. The key of nursing care is prevention and care of infection, observation of serum sickness reaction and liver function in order to insure effectiveness and safetyduring treatment. Key words: Crohn's disease; Infliximab; Adverse reactions; Nursing
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